The Conradt and Lambie Lab

• Haeussler, S., Yeroslaviz, A., Rolland, S. G., Luehr, S., Lambie, E. J., & Conradt, B. (2021). Genome-wide RNAi screen for regulators of UPRmt in Caenorhabditis elegans mutants with defects in mitochondrial fusion. G3 (Bethesda). doi:10.1093/g3journal/jkab095
• van Veen, S., Martin, S., Van den Haute, C., Benoy, V., Lyons, J., Vanhoutte, R., . . . Vangheluwe, P. (2020). ATP13A2 deficiency disrupts lysosomal polyamine export. Nature, 578, 419-424. doi:10.1038/s41586-020-1968-7
• Vrijsen, S., Besora-Casals, L., van Veen, S., Zielich, J., Van den Haute, C., Hamouda, N. N., . . . Vangheluwe, P. (2020). ATP13A2-mediated endo-lysosomal polyamine export counters mitochondrial oxidative stress. Proc Natl Acad Sci U S A. doi:10.1073/pnas.1922342117
• Wei, H., Lambie, E. J., Osório, D. S., Carvalho, A. X., & Conradt, B. (2020). PIG-1 MELK-dependent phosphorylation of nonmuscle myosin II promotes apoptosis through CES-1 Snail partitioning. PLoS Genet, 16 (9), e1008912. doi:10.1371/journal.pgen.1008912
• Rolland, S. G., Schneid, S., Schwarz, M., Rackles, E., Fischer, C., Haeussler, S., . . . Conradt, B. (2019). Compromised Mitochondrial Protein Import Acts as a Signal for UPRmt. Cell Reports. doi:10.1016/j.celrep.2019.07.049
• Zielich, J., Tzima, E., Schröder, E. A., Jemel, F., Conradt, B., & Lambie, E. J. (2018). Overlapping expression patterns and functions of three paralogous P5B ATPases in Caenorhabditis elegans. PLoS ONE, 13 (3), e0194451. doi:10.1371/journal.pone.0194451
• Lambie, E. J., & Conradt, B. (2016). Deadly dowry: how engulfment pathways promote cell killing. CELL DEATH AND DIFFERENTIATION, 23 (4), 553-554. doi:10.1038/cdd.2015.170
• Chakraborty, S., Lambie, E. J., Bindu, S., Mikeladze-Dvali, T., & Conradt, B. (2015). Engulfment pathways promote programmed cell death by enhancing the unequal segregation of apoptotic potential. NATURE COMMUNICATIONS, 6, ARTN 10126. doi:10.1038/ncomms10126
• Lambie, E. J., Bruce, R. D., Zielich, J., & Yuen, S. N. (2015). Novel Alleles of gon-2, a C. elegans Ortholog of Mammalian TRPM6 and TRPM7, obtained by genetic reversion screens. PLoS ONE, 10 (11). doi:10.1371/journal.pone.0143445
• Hollopeter, G., Lange, J. J., Zhang, Y., Vu, T. N., Gu, M., Ailion, M., . . . Jorgensen, E. M. (2014). The membrane-associated proteins FCHo and SGIP are allosteric activators of the AP2 clathrin adaptor complex. eLife, 3. doi:10.7554/eLife.03648
• Lambie, E. J., Tieu, P. J., Lebedeva, N., Church, D. L., & Conradt, B. (2013). CATP-6, a C. elegans Ortholog of ATP13A2 PARK9, Positively Regulates GEM-1, an SLC16A Transporter. PLOS ONE, 8 (10), ARTN e77202. doi:10.1371/journal.pone.0077202
• Lambie, E. J. (2011). Mapping Mutations in C. elegans. CAENORHABDITIS ELEGANS: MOLECULAR GENETICS AND DEVELOPMENT, SECOND EDITION, 106, 3-22. doi:10.1016/B978-0-12-544172-8.00001-3
• Teramoto, T., Sternick, L. A., Kage-Nakadai, E., Sajjadi, S., Siembida, J., Mitani, S., . . . Lambie, E. J. (2010). Magnesium Excretion in C. elegans Requires the Activity of the GTL-2 TRPM Channel. PLOS ONE, 5 (3), A228-A235. doi:10.1371/journal.pone.0009589
• Kemp, B. J., Church, D. L., Hatzold, J., Conradt, B., & Lambie, E. J. (2009). gem-1 Encodes an SLC16 Monocarboxylate Transporter-Related Protein That Functions in Parallel to the gon-2 TRPM Channel During Gonad Development in Caenorhabditis elegans. GENETICS, 181 (2), 581-591. doi:10.1534/genetics.108.094870
• Kemp, B. J., Hatzold, J., Sternick, L. A., Cornman-Homonoff, J., Whitaker, J. M., Tieu, P. J., & Lambie, E. J. (2007). In vivo construction of recombinant molecules within the Caenorhabditis elegans germ line using short regions of terminal homology. NUCLEIC ACIDS RESEARCH, 35 (19), ARTN e133. doi:10.1093/nar/gkm857
• Lee, M. -. H., Ohmachi, M., Arur, S., Nayak, S., Francis, R., Church, D., . . . Schedl, T. (2007). Multiple functions and dynamic activation of MPK-1 extracellular signal-regulated kinase signaling in Caenorhabditis elegans germline development. GENETICS, 177 (4), 2039-2062. doi:10.1534/genetics.107.081356
• Chen, C. C. H., Schweinsberg, P. J., Vashist, S., Mareiniss, D. P., Lambie, E. J., & Grant, B. D. (2006). RAB-10 is required for endocytic recycling in the Caenorhabditis elegans intestine. MOLECULAR BIOLOGY OF THE CELL, 17 (3), 1286-1297. doi:10.1091/mbc.e05-08-0787
• Teramoto, T., Lambie, E. J., & Iwasaki, K. (2005). Differential regulation of TRPM channels governs electrolyte homeostasis in the C. elegans intestine. CELL METABOLISM, 1 (5), 343-354. doi:10.1016/j.cmet.2005.04.007
• Church, D. L., & Lambie, E. J. (2003). The promotion of gonadal cell divisions by the Caenorhabditis elegans TRPM cation channel GON-2 is antagonized by GEM4 copine. GENETICS, 165 (2), 563-574.
• Ohmachi, M., Rocheleau, C. E., Church, D., Lambie, E., Schedl, T., & Sundaram, M. V. (2002). C-elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation. CURRENT BIOLOGY, 12 (5), 427-433. doi:10.1016/S0960-9822(02)00690-5
• Hsu, V., Zobel, C. L., Lambie, E. J., Schedl, T., & Kornfeld, K. (2002). Caenorhabditis elegans lin-45 raf is essential for larval viability, fertility and the induction of vulval cell fates. GENETICS, 160 (2), 481-492.
• Lambie, E. J. (2002). Cell proliferation and growth in C-elegans. BIOESSAYS, 24 (1), 38-53. doi:10.1002/bies.10019
• West, R. J., Sun, A. Y., Church, D. L., & Lambie, E. J. (2001). The C-elegans gon-2 gene encodes a putative TRP cation channel protein required for mitotic cell cycle progression. GENE, 266 (1-2), 103-110. doi:10.1016/S0378-1119(01)00373-0
• Beitel, G. J., Lambie, E. J., & Horvitz, H. R. (2000). The C-elegans gene lin-9, which acts in an Rb-related pathway, is required for gonadal sheath cell development and encodes a novel protein. GENE, 254 (1-2), 253-263. doi:10.1016/S0378-1119(00)00296-1
• Gumienny, T. L., Lambie, E., Hartwieg, E., Horvitz, H. R., & Hengartner, M. O. (1999). Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline. DEVELOPMENT, 126 (5), 1011-1022.
• Kadyk, L. C., Lambie, E. J., & Kimble, J. (1997). glp-3 is required for mitosis and meiosis in the Caenorhabditis elegans germ line. GENETICS, 145 (1), 111-121.
• Sun, A. Y., & Lambie, E. J. (1997). gon-2, a gene required for gonadogenesis in Caenorhabditis elegans. GENETICS, 147 (3), 1077-1089.
• Lambie, E. J. (1997). Nematode development: Evolutionary detours of a pivotal cell. CURRENT BIOLOGY, 7 (3), R160-R163. doi:10.1016/S0960-9822(97)70078-2
• Lambie, E. J. (1996). Cell-cell communication: Receptor function at the junction. CURRENT BIOLOGY, 6 (9), 1089-1091. doi:10.1016/S0960-9822(02)70674-X
• CHURCH, D. L., GUAN, K. L., & LAMBIE, E. J. (1995). 3 GENES OF THE MAP KINASE CASCADE, MEK-2, MPK-1/SUR-1 AND LET-60 RAS, ARE REQUIRED FOR MEIOTIC CELL-CYCLE PROGRESSION IN CAENORHABDITIS-ELEGANS. DEVELOPMENT, 121 (8), 2525-2535.
• HENDERSON, S. T., GAO, D., LAMBIE, E. J., & KIMBLE, J. (1994). LAG-2 MAY ENCODE A SIGNALING LIGAND FOR THE GLP-1 AND LIN-12 RECEPTORS OF C-ELEGANS. DEVELOPMENT, 120 (10), 2913-2924.
• LAMBIE, E. J. (1994). NEMATODE DEVELOPMENT – VARIATIONS ON A VULVAR THEME. CURRENT BIOLOGY, 4 (12), 1128-1130. doi:10.1016/S0960-9822(00)00254-2
• MANGO, S. E., LAMBIE, E. J., & KIMBLE, J. (1994). THE PHA-4 GENE IS REQUIRED TO GENERATE THE PHARYNGEAL PRIMORDIUM OF CAENORHABDITIS-ELEGANS. DEVELOPMENT, 120 (10), 3019-3031.
• MANGO, S. E., LAMBIE, E. J., & KIMBLE, J. (1994). THE PHA-4 LOCUS AND ORGAN IDENTITY IN C-ELEGANS. DEVELOPMENTAL BIOLOGY, 163 (2), 536. ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS.
• XIE, K. W., LAMBIE, E. J., & SNYDER, M. (1993). NUCLEAR DOT ANTIGENS MAY SPECIFY TRANSCRIPTIONAL DOMAINS IN THE NUCLEUS. MOLECULAR AND CELLULAR BIOLOGY, 13 (10), 6170-6179. doi:10.1128/MCB.13.10.6170
• YANG, C. H., LAMBIE, E. J., & SNYDER, M. (1992). NUMA – AN UNUSUALLY LONG COILED-COIL RELATED PROTEIN IN THE MAMMALIAN NUCLEUS. JOURNAL OF CELL BIOLOGY, 116 (6), 1303-1317. doi:10.1083/jcb.116.6.1303
• KIMBLE, J., CRITTENDEN, S., LAMBIE, E., KODOYIANNI, V., MANGO, S., & TROEMEL, E. (1992). REGULATION OF INDUCTION BY GLP1, A LOCALIZED CELL-SURFACE RECEPTOR IN CAENORHABDITIS-ELEGANS. COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 57, 401-407. COLD SPRING HARBOR LAB PRESS. doi:10.1101/SQB.1992.057.01.045
• LAMBIE, E. J., & KIMBLE, J. (1991). 2 HOMOLOGOUS REGULATORY GENES, LIN-12 AND GLP-1, HAVE OVERLAPPING FUNCTIONS. DEVELOPMENT, 112 (1), 231-240.
• LAMBIE, E. J., & KIMBLE, J. (1991). GENETIC-CONTROL OF CELL-INTERACTIONS IN NEMATODE DEVELOPMENT (Vol. 25). ANNUAL REVIEWS.
• LAMBIE, E. J., & KIMBLE, J. (1991). LIN-12 AND GLP-1 – HOMOLOGOUS GENES WITH OVERLAPPING FUNCTIONS IN CAENORHABDITIS-ELEGANS. CELL-CELL INTERACTIONS IN EARLY DEVELOPMENT, 283-296. WILEY-LISS, INC.
• ROCKMILL, B., LAMBIE, E. J., & ROEDER, G. S. (1991). SPORE ENRICHMENT. METHODS IN ENZYMOLOGY, 194, 146-149.
• YANG, C. H., LAMBIE, E. J., HARDIN, J., CRAFT, J., & SNYDER, M. (1989). HIGHER-ORDER STRUCTURE IS PRESENT IN THE YEAST NUCLEUS – AUTOANTIBODY PROBES DEMONSTRATE THAT THE NUCLEOLUS LIES OPPOSITE THE SPINDLE POLE BODY. CHROMOSOMA, 98 (2), 123-128. doi:10.1007/BF00291048
• LAMBIE, E. J., & ROEDER, G. S. (1988). A YEAST CENTROMERE ACTS IN CIS TO INHIBIT MEIOTIC GENE CONVERSION OF ADJACENT SEQUENCES. CELL, 52 (6), 863-873. doi:10.1016/0092-8674(88)90428-X
• LAMBIE, E. J., & ROEDER, G. S. (1986). REPRESSION OF MEIOTIC CROSSING OVER BY A CENTROMERE (CEN3) IN SACCHAROMYCES-CEREVISIAE. GENETICS, 114 (3), 769-789.
• ROEDER, G. S., SMITH, M., & LAMBIE, E. J. (1984). INTRACHROMOSOMAL MOVEMENT OF GENETICALLY MARKED SACCHAROMYCES-CEREVISIAE TRANSPOSONS BY GENE CONVERSION. MOLECULAR AND CELLULAR BIOLOGY, 4 (4), 703-711. doi:10.1128/MCB.4.4.703
• Wei, H., Lambie, E. J., Osório, D. S., Carvalho, A. X., & Conradt, B. (n.d.). PIG-1 MELK-dependent phosphorylation of nonmuscle myosin II promotes apoptosis through CES-1 Snail partitioning. Cold Spring Harbor Laboratory. doi:10.1101/2020.06.04.133983